New Tools for Proteostasis Research
About Us
The Proteostasis Consortium is a group of investigators who have worked together on proteostasis in biology, health, and diseases. Together, we have contributed fundamental insights on biochemical mechanisms of protein quality control, on cellular and organismal processes, the effects of healthy and unhealthy aging, disease mechanisms, and the development of therapeutic approaches to suppress or delay diseases of protein conformation.
Members of the Proteostasis Consortium include Steve Finkbeiner at the Gladstone Institutes at the University of California San Francisco, Dan Finley at Harvard Medical School, Judith Frydman at Stanford University, Jason Gestwicki at the University of California San Francisco, Jeff Kelly at The Scripps Research Institute, Richard I. Morimoto at Northwestern University, Evan Powers at The Scripps Research Institute, and Miguel Prado at the Instituto de Investigación Sanitari del Principado de Asturia.
We are funded by many sources including the NIH, the Hevolution Foundation, and The Rainwater Charitable Foundation.
Team of Scientists
Steven Finkbeiner, MD, PhD
Director, Center for Systems and
Therapeutics & Taube/Koret Center
for Neurodegenerative Disease,
Gladstone Institutes
Professor, Departments of
Neurology and Physiology,
University of California, San Francisco
Daniel Finley, PhD
Professor of Cell Biology
Harvard Medical School
Judith Frydman, PhD
Donald Kennedy Chair in the School of Humanities and Sciences
Professor of Genetics and Biology
Stanford University
Jason Gestwicki, PhD
Associate Director of Academic Affairs
Professor, Department of Pharmaceutical Chemistry
University of California, San Francisco
Jeffery Kelly, PhD
Lita Annenberg Hazen Professor of Chemistry
The Scripps Research Institute
Richard I. Morimoto, PhD
Bill and Gayle Cook Professor of Biology
Director, Rice Institute for
Biomedical Research
Department of Molecular Biosciences, Northwestern University
Evan Powers, PhD
Institute Investigator
Department of Chemistry
California Campus
Scripps Research
Miguel Prado, PhD
Institute Investigator
Proteomics and Proteostasis group
Asturias, Spain
Health Research Institute of Asturias (ISPA)
Announcements
2024 Proteostasis Consortium Seminar Series Schedule
| Date | Speaker | Institution | Seminar Title |
|---|---|---|---|
| January 10, 2024 | Jaroslaw (Jarek) Marszalek | University of Gdańsk | Hsp70’s client binding cycle - insights from dissecting a highly specialized system |
| January 17, 2024 | Alessandro Ori | Genentech Inc. | The Aging Proteome |
| January 24, 2024 | Vadim Gladyshev | Harvard Medical School | Insights on aging, longevity and rejuvenation |
| February 21, 2024 | Elizabeth Rhoades | University of Pennsylvania | Modifying α-Synuclein to modulate function |
| February 28, 2024 | Ramanujan Hegde | MRC Laboratory of Molecular Biology | Biogenesis of the membrane proteome |
| April 17, 2024 | Yogesh Kulathu | University of Dundee | Regulation of ER homeostasis by UFM1, the enigmatic ubiquitin-like modifier |
| April 24-28, 2024 | Meeting registration | COLD SPRING HARBOR | Protein Homeostasis in Health and Disease |
| May 08, 2024 | Claudio Joazeiro | Center for Molecular Biology of Heidelberg University (ZMBH) | Ribosome-associated Quality Control (RQC): mechanisms, evolution, and role in neurodegeneration |
| May 22, 2024 | Barry Willardson | Brigham Young University | Visualizing chaperonin-mediated protein folding |
| June 12, 2024 | Christian Münch | Goethe University Frankfurt – Medical School | Mitochondrial protein quality control |
| July 7-11, 2024 | Meeting registration | FASEB | Protein Folding in the Cell |
| November 06, 2024 | Ivan Dikic | Goethe University Frankfurt | Pathogenic Proteotoxicity of Cryptic Splicing |
| November 13, 2024 | Rahul Samant | Babraham Institute | Divergent proteostasis strategies underpin senescent cellular states |
| December 18, 2024 | Brian Freeman | University of Illinois Urbana-Champaign | The shifting physical interactome of Hsp90 during chronological aging |
| January 29, 2025 | Andrew Truman | University of North Carolina at Charlotte | Understanding the reciprocal interplay between the Hsp70 chaperone code and proteostasis |
| February 26, 2025 | Christina Woo | Harvard University | Investigation of protein damage modifications |
PROTEOSTASIS CONSORTIUM WEEKLY SEMINAR SERIES (VIA ZOOM)
VIEW FULL SCHEDULE UNDER SEMINARS
RECORDINGS WILL BE POSTED 3 WEEKS AFTER LIVE SEMINAR DATE UNDER SEMINARS
Contact: Rebecca (rebecca.phend@northwestern.edu)
Principal Investigators
Contact Us
Proteostasis Consortium
Grant and Website Administrator
Rebecca Phend (rebecca.phend@northwestern.edu)
