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2022 Seminars

2022 Seminars

 

JAN 12, 2022 – ADAM ANTEBI (MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING)

     Nucleolar regulation of longevity

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JAN 19, 2022 – SHIGEO MURATA (THE UNIVERSITY OF TOKYO)

     Mechanisms that respond to proteasome dysfunction

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JAN 26, 2022 – ANDREAS MARTIN (UNIVERSITY OF CALIFORNIA, BERKELEY)

      Beyond just targeting: Ubiquitin modulates the conformational changes and substrate degradation of the 26S proteasome

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FEB 02, 2022 – GILLIAN BATES (UCL QUEEN SQUARE INSTITUTE OF NEUROLOGY)

     Targeting huntingtin as a therapeutic strategy for Huntington’s disease

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FEB 09, 2022 – LEWIS KAY (UNIVERSITY OF TORONTO)

     Solution NMR Reveals the Critical Role of Dynamics in Driving the Function of Molecular Machines

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FEB 16, 2022 – KIM ORTH (UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER)

    From flies to mice: Fic-mediated AMPylation of BiP is an evolutionarily conserved mechanism used to tune a physiological response to stress in animals

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FEB 23, 2022 – ADAM FROST (UCSF)

     Membrane-Associated Quality Control Mechanisms

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MARCH 02, 2022 – HILAL LASHUEL (EPFL)

     Rethinking drug discovery in neurodegenerative diseases: Challenges and opportunities

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MARCH 09, 2022 – SUSAN FERRO-NOVICK (UCSD)

     ER-phagy limits the accumulation of misfolded protein condensates in the endoplasmic reticulum

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MARCH 16, 2022 – ANA MARIA CUERVO (ALBERT EINSTEIN COLLEGE OF MEDICINE)

     Selective autophagy in aging and age-related diseases

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MARCH 23, 2022 – EVAN POWERS (SCRIPPS RESEARCH)

     The Proteostasis Network: Lists and Lessons

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MARCH 30, 2022 – JOEL BUXBAUM (SCRIPPS RESEARCH)

    Chaperones outside the cell: Professionals, Talented Amateurs, or Accidental Tourists

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APRIL 06, 2022 – CHRISTINE VOGEL (NEW YORK UNIVERSITY)

The ups and downs of protein expression regulation in response to misfolding stress

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APRIL 13, 2022 – MARTIN KAMPMANN (UCSF)

    Uncovering mechanisms controlling protein aggregation by CRISPR-based functional genomics

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APRIL 20, 2022 – CARMELA SIDRAUSKI (CALICO)

     Mechanisms and Pathophysiology of the Integrated Stress Response

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APRIL 27, 2022 – COLD SPRING HARBOR MEETING

     Protein Homeostasis in Health and Disease

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MAY 04, 2022 – NO SEMINAR

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MAY 11, 2022 – WILLIAM BALCH (SCRIPPS RESEARCH)

     Understanding Proteostasis through Gaussian Process Regression Machine Learning

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MAY 18, 2022 – JOHN COLLINGE (UNIVERSITY COLLEGE LONDON INSTITUTE OF PRION DISEASE AND MRC PRION UNIT)

      Understanding prion structure, strains and neurotoxicity

     *no recording will be posted

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MAY 25, 2022 – VEENA PRAHLAD (UNIVERSITY OF IOWA)

     Linking cellular stress responses to systemic physiology: mechanisms and consequences

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JUNE 1, 2022 – RON KOPITO (STANFORD UNIVERSITY)

     UFMylation and ribosome quality control at the endoplasmic reticulum

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JUNE 8, 2022 – AIMEE KAO (UCSF)

Aging, Lysosomes and Neurodegenerative Disease

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JUNE 15, 2022 – SHU-OH SHAN (CALTECH)

Decision making at early stages of protein biogenesis

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JUNE 22, 2022 – WALID HOURY (UNIVERSITY OF TORONTO)

     Development of novel anticancer compounds dysregulating protein homeostasis by targeting the human mitochondrial ClpP protease

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JUNE 29, 2022 – RANDY HAMPTON (UCSD)

Leveraging Protein Quality Control for Biological Regulation: Mallostery and Metabolism

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JULY 06, 2022 – STEVEN JOHNSON (INDIANA UNIVERSITY SCHOOL OF MEDICINE)

     Exploring in vitro and intracellular inhibitor mechanisms to establish if GroEL/ES and HSP60/10 chaperonin systems are “druggable” targets

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JULY 13, 2022 – FASEB CONFERENCE  – July 10–15, 2022 – Malahide, Ireland

     The Protein Folding in the Cell Conference

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JULY 20, 2022 – CONRAD (CHRIS) WEIHL (WASHINGTON UNIVERSITY)

     Chaperonopathies associated with HSP40 mutations

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JULY 27, 2022 – JOHN YATES (SCRIPPS RESEARCH)

     Cystic Fibrosis Ion Transport Regulator

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AUGUST 3-31, 2022 – NO SEMINARS FOR THE MONTH OF AUGUST. ENJOY YOUR SUMMER!

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SEPTEMBER 7, 2022 – DANIEL SOUTHWORTH (UCSF)

     The structure and function of AAA+ protein disaggregase machines elucidated by cryo-EM

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SEPTEMBER 14, 2022 – STEVE FINKBEINER (GLADSTONE INSTITUTES)

Applications of Deep Learning for Proteostasis and Neurodegeneration Research

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SEPTEMBER 21, 2022 – NANCY BONINI (UNIVERSITY OF PENNSYLVANIA)

     Regulation of the stress response of the Drosophila brain by m⁶A

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SEPTEMBER 28, 2022 

LARS PLATE (VANDERBILT UNIVERSITY)

Time-Resolved Interactomics to Elucidate Proteostasis Dynamics

and

SUE ANN MOK (UNIVERSITY OF ALBERTA)

Exploring the mutability of tau aggregate structures

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OCTOBER 5, 2022 – RALPH (RANDY) NIXON (NYU)

     Lysosome Dysfunction – a primary catalyst in Alzheimer’s Disease

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OCTOBER 12, 2022 – ELLEN NOLLEN (GRONINGEN UNIVERSITY)

    Cellular mechanisms of protein aggregation and toxicity

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OCTOBER 19, 2022 –

MATTHEW SCAGLIONE (DUKE UNIVERSITY)

SCA48 mutations reveal metamorphic properties of the E3 ligase CHIP

and

AMANDA WOERMAN (UNIVERSITY OF MASSACHUSETTS AMHERST)

Alpha-synuclein strain biology in multiple system atrophy

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NOVEMBER 2, 2022 – MARINA RODNINA (MAX PLANK INSTITUTE FOR BIOPHYSICAL CHEMISTRY, GÖTTINGEN)

    Cotranslational protein folding

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NOVEMBER 9, 2022 – JUDITH STEEN (HARVARD MEDICAL SCHOOL)

    Tauopathy and Dementia: A story of Mice and (Wo)Men

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NOVEMBER 30, 2022 – No seminar

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DECEMBER 7, 2022 – NORA VOEGTLE (HEIDELBERG UNIVERSITY )

    Cellular responses to mitochondrial proteotoxic stress

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DECEMBER 14, 2022 – JEFF KELLY (SCRIPPS RESEARCH)

    Proteostasis Regulators to Ameliorate Loss-of-Function Proteinopathies

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